Fertility drugs regulate or stimulate ovulation. Fertility drugs are the main treatment for women who are infertile due to ovulation disorders. Fertility drugs generally work like the natural hormones follicle-stimulating hormone (FSH) and luteinizing hormone (LH) to trigger ovulation.
After five days of taking clomiphene, your brain releases a "surge" of luteinizing hormone (LH), which signals the ovaries to release one or more mature eggs from the follicles when you ovulate. The LH surge happens five to 12 days after you takethe last clomiphene pill.